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ABOUT US
About Rota
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Antimicrobial Peptides
Epidermal Growth Factor
Trefoil Factor Peptides
FAQ
Rota Articles
Antimicrobial Peptides FAQ
Epidermal Growth Factor FAQ
Trefoil Factor Peptides FAQ
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ECOTIDE Detection Methods
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Cattle and Sheep 100 Questions Ⅰ
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Very basic ruminant farming FAQ, will continue to update.
Pig Prices Continue to Remain Low ▏Increased Pressure on Breeding Companies
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The reduction in pig production capacity in the fourth quarter will be realized in the reduction of pig supply after the third quarter of 2024, when pig prices may recover.
Broiler International/China Market Supply and Demand Analysis
Strategic Management of Future Lactating Herds
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If you want to know how to improve the milk yield of your dairy herd in the future, you are encouraged to click this article.
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With the rapid rise in the emergence of bacterial strains resistant to multiple classes of antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to combat these pathogens.
How TFFs Work?
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TFF3 rapid responds to injury, and it can reduce intestinal epithelial permeability by regulating tight junctions (FIG.2), an effect that can be attenuated by inhibition of the PI3K/AKT signaling pathway. In addition, the process of restitution requires TFF3 to act as a motogen, by promoting epithelial cell elongation and migration to cover the exfoliated surface.Studies have shown that TFF3 treatment enhances the collective migration of IEC-18 cells and forms continuous sheets of migrating cells to ensure precise coverage of the re-populated area. It is suggested that TFF3 may promote intestinal mucosal reconstitution through crosstalk between ERK and JAK/signal transducer and activator of transcription (STAT3) pathways.[2]
Learn about Trefoil Factor Family Peptides (TFFs)
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The trefoil factor family (TFF) is a relatively new family of polypeptides with a three-loop trefoil domain. They are mainly synthesized and secreted by the protein-secreting epithelial cells of the gastrointestinal mucosa and are closely related to mucins. Their abundant expression in different patterns under normal conditions, physiological state under different ulcer conditions and ectopic expression suggest that they play an important role in mucosal defense and repair.
What Happens in the Case of Infection?
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Studies have found that when animals are infected or attacked by pathogenic microorganism, the corresponding secretion of antimicrobial peptides in the body will increase sharply (100-1000 times) to fight inflammation.
Understand the Role of Defensins Correctly
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Defensins, which belongs to the host defense peptide, are defensive molecule for early defense response of mammalian mucosal immunity, and are important components of the innate immune system. Defensins not only directly kill invade pathogenic microorganisms, but also indirectly kill them by activating the immune system.
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Defensins, as a natural broad-spectrum antimicrobial substance, have obvious bactericidal effects on most microorganisms in vitro and vivo experiments. However, in the vivo environment, the role of defensin can be selective.
Home > Rota Articles
Cattle and Sheep 100 Questions  Ⅰ

Cattle and Sheep 100 Questions Ⅰ

Dec 01, 2023

12-012023

Very basic ruminant farming FAQ, will continue to update.
Pig Prices Continue to Remain Low ▏Increased Pressure on Breeding Companies

Pig Prices Continue to Remain Low ▏Increased Pressure on Breeding Companies

Nov 13, 2023

11-132023

The reduction in pig production capacity in the fourth quarter will be realized in the reduction of pig supply after the third quarter of 2024, when pig prices may recover.
Broiler International/China Market Supply and Demand Analysis

Broiler International/China Market Supply and Demand Analysis

Nov 08, 2023

11-082023

Strategic Management of Future Lactating Herds

Strategic Management of Future Lactating Herds

Oct 27, 2023

10-272023

If you want to know how to improve the milk yield of your dairy herd in the future, you are encouraged to click this article.
Multifunctional Cationic Host Defence Peptides and Their Clinical Applications

Multifunctional Cationic Host Defence Peptides and Their Clinical Applications

Sep 20, 2023

09-202023

With the rapid rise in the emergence of bacterial strains resistant to multiple classes of antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to combat these pathogens.
Milk-Born Bioactive Peptide-EGF and Its Intestinal Protection ChapterⅠ

Milk-Born Bioactive Peptide-EGF and Its Intestinal Protection ChapterⅠ

Mar 22, 2023

03-222023

The gastrointestinal tract is a complex organ that undergoes many substantial changes early in its formation.
Milk-Born Bioactive Peptide-EGF and Its Intestinal Protection--ChapterⅡ

Milk-Born Bioactive Peptide-EGF and Its Intestinal Protection--ChapterⅡ

Mar 23, 2023

03-232023

In the intestine, EGF can enhance the proliferation and differentiation of epithelial cells, and has a significant effect on the repair of the damaged intestinal mucosa and intestinal adaptation.
Milk-Born Bioactive Peptide-EGF and Its Intestinal Protection--Chapter III

Milk-Born Bioactive Peptide-EGF and Its Intestinal Protection--Chapter III

Apr 28, 2023

04-282023

EGF levels in milk of mothers with extremely pre-term neonates are 50-80% higher compared with those in milk of mothers
Intestine Microbiome, Metabolism and Host Immunity--Chapter Ⅰ

Intestine Microbiome, Metabolism and Host Immunity--Chapter Ⅰ

Mar 22, 2023

03-222023

The microbiome is the collection of microorganisms that live in and on all mammals that provide important signals for the development and function of the immune system
Intestine Microbiome, Metabolism and Host Immunity--Chapter Ⅱ

Intestine Microbiome, Metabolism and Host Immunity--Chapter Ⅱ

Mar 22, 2023

03-222023

Describe The Composition of Microorganisms, Study the Function of Microorganisms
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